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  • Yu Fenglei, MD, Profesor Bedah Toraks

    Yu Fenglei, MD, Profesor Bedah Toraks

    MD, Profesor Bedah Toraks

    Pengobatan kanker paru-paru dan kanker kerongkongan


    Profesor Yu Fenglei adalah seorang ahli bedah toraks terkenal di Tiongkok. Beliau adalah direktur departemen bedah toraks dan direktur kantor penelitian bedah toraks di Rumah Sakit Xiangya Kedua di Central South University.

    Beliau memiliki spesialisasi dalam tumor toraks selama lebih dari 30 tahun dan memiliki pengetahuan mendalam dalam pengobatan penyakit bedah toraks yang kompleks. Ahli bedah tersebut telah berhasil menyelesaikan ratusan operasi kompleks yang langka dan parah, seperti reseksi dan rekonstruksi massa besar di dada dan punggung dan reseksi dan reseksi esofagus secara simultan yang melibatkan trakea dan proses desendens. Rekonstruksi trakea, reseksi parsial dan rekonstruksi tumor ganas yang melibatkan aorta, perbaikan dan rekonstruksi fistula esofagus + aorta, reseksi parsial atrium kiri tanpa bypass kardiopulmoner, trakeoplasti dan rekonstruksi setelah trakeektomi ultra-panjang, transplantasi paru ganda berurutan tanpa bypass kardiopulmoner, transplantasi paru autologus, dll.


    Arah Penelitian

    1. Kombinasi pengobatan Imunoterapi untuk kanker paru stadium lanjut

    2. Pengembangan dan penerapan klinis trakea buatan

    3. Perawatan bedah penyakit bedah toraks yang parah dan kompleks

    4. Penelitian mekanisme anemia terkait tumor

    5. Penelitian teknologi deteksi ctDNA pada darah tepi kanker paru

    6. Penelitian teknologi isolasi, penangkapan dan identifikasi CTC darah tepi pada kanker paru

    Bagian Makalah:

    1. Wei-Yu,Yang,Yu,He,Muyun,Peng,Zhe,Zhang,Shouzhi,Xie,Zeyu,Wu,Qikang,Hu,Fenglei,Yu.Thermal ablation versus radiotherapy for inoperable stage III non-small cell lung cancer: a propensity score matching analysis.[J].International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group,2023,40(1):2154577.DOI:10.1080/02656736.2022.2154577.

    2. Cheng,Wang,Qikang,Hu,Yi,Sun,Fenglei,Yu,Muyun,Peng.Complete pathological remission after neoadjuvant ensartinib in patients with locally advanced lung adenocarcinoma and with CTLC-ALK and ALK-DHX8 rearrangements.[J].European journal of cancer (Oxford, England : 1990),2022,169:131-134.DOI:10.1016/j.ejca.2022.04.012.

    3. Wei-Yu,Yang,Yu,He,Qikang,Hu,Muyun,Peng,Zhe,Zhang,Shouzhi,Xie,Fenglei,Yu.Survival benefit of thermal ablation therapy for patients with stage II-III non-small cell lung cancer: A propensity-matched analysis.[J].Frontiers in oncology,2022,12:984932.DOI:10.3389/fonc.2022.984932.

    4. Zhenyu,Zhao,Banglun,Qian,Xiong,Peng,Wei,Yin,Qidong,Cai,Pengfei,Zhang,Boxue,He,Shuai,Shi,Weilin,Peng,Guangxu,Tu,Yunping,Li,Yongguang,Tao,Xiang,Wang,Fenglei,Yu.Metagenomic analysis of the microbiome of lung adenocarcinoma with pure ground-glass opacity.[J].Clinical and translational medicine,2022,12(1):e698.DOI:10.1002/ctm2.698.

    5. Bin,Wang,Zhe,Zhang,Yuanwei,Guo,Fenglei,Yu.Trachea repair using an autologous pericardial patch combined with a 3D carbon fiber stent: A case report.[J].Frontiers in surgery,2022,9:1086792.DOI:10.3389/fsurg.2022.1086792.

    6. Yan,Hu,Siying,Ren,Lulu,Yang,Zhongyi,Tong,Ruoyao,Wang,Wei,Han,Chao,Zeng,Jina,Li,Peng,Xiao,Li,Wang,Fenglei,Yu,Wenliang,Liu.Osimertinib as Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer: A Case Series.[J].Frontiers in pharmacology,2022,13:912153.DOI:10.3389/fphar.2022.912153.

    7. Yan,Hu,Siying,Ren,Chao,Zeng,Jina,Li,Min,Zou,Li,Wang,Peng,Xiao,Fenglei,Yu,Wenliang,Liu.Case Report: Surgical Therapy for Left Innominate Vein Aneurysm Under Thoracoscopy.[J].Frontiers in surgery,2021,8:741840.DOI:10.3389/fsurg.2021.741840.

    8. Yan,Hu,Siying,Ren,Chen,Chen,Qingchun,Liang,Fenglei,Yu,Wenliang,Liu.Metachronous primary lung adenocarcinomas harboring distinct KRAS mutations.[J].Thoracic cancer,2020,11(7):2018-2022.DOI:10.1111/1759-7714.13458.

    9. Muyun,Peng,Xiang,Wang,Chen,Chen,Sichuang,Tan,Wenliang,Liu,Fenglei,Yu.Report on 153 sequential three-incision robotic-assisted pulmonary resections by a single surgeon: technical details and learning curve.[J].Journal of thoracic disease,2020,12(3):741-748.DOI:10.21037/jtd.2019.12.116.

    10. Yin, Wei,Wang, Xiang,Li, Yunping,Wang, Bin,Song, Mingzhe,Hulbert, Alicia,Chen, Chen,Yu, Fenglei.Promoter hypermethylation of cysteine dioxygenase type 1 in patients with non-small cell lung cancer[J].Oncology letters,2020,20(1 Pt.B):967-973.

    11. Muyun Peng,Yuancai Xie,Xiaohua Li,Youhui Qian,Xiaonian Tu,Xumei Yao,Fangsheng Cheng,Feiyue Xu,Deju Kong,Bing He,Chaoyu Liu,Fengjun Cao,Haoxian Yang,Fenglei Yu,Chuanbo Xu,Geng Tian.Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA[J].Journal of Medical Genetics,2019,56(10):647-653.

    12. Bin,Wang,Xilong,Mei,Wenliang,Liu,Fenglei,Yu.Chest wall reconstruction with 3-dimensional custom-made carbon fiber ribs.[J].The Journal of thoracic and cardiovascular surgery,2018,156(4):e177-e179.DOI:10.1016/j.jtcvs.2018.05.070.

    13. Bin,Wang,Sichuang,Tan,Fenglei,Yu.Correction of postpneumonectomy syndrome with tridimensional carbon fiber-printed implant.[J].The Journal of thoracic and cardiovascular surgery,2018,155(4):e135-e137.DOI:10.1016/j.jtcvs.2017.11.081.

    14. Wang, Bin,Tan, Sichuang,Yu, Fenglei.Correction of postpneumonectomy syndrome with tridimensional carbon fiber-printed implant[J].The Journal of Thoracic and Cardiovascular Surgery,2018,155(4):E135-E137.

    15. Bin Wang,Xilong Mei,Wenliang Liu,Fenglei Yu.Chest wall reconstruction with 3-dimensional custom-made carbon fiber ribs[J].The Journal of Thoracic and Cardiovascular Surgery,2018,156(4):e177-e179.

    16. Hu, Huali,Liu, Wenliang,Battafarano, Richard J.,Chen, Chen,Tang, Jingqun,Tan, Sichuang,Peng, Muyun,Yu, Fenglei.Extralobar Aneurysm of Intralobar Pulmonary Sequestration Artery Originating From Aorta Arch[J].The Annals of Thoracic Surgery: Official Journal of the Society of Thoracic Surgeons and the Southern Thoracic Surgical Association,2016,101(4):E121-E121.

    17. Chen,Chen,Xiaojie,Huang,Mingjiu,Chen,Fenglei,Yu,Bangliang,Yin,Yunchang,Yuan.Surgical management of a giant sternal chondromyxoid fibroma: a case report.[J].Journal of cardiothoracic surgery,2015,10:178.DOI:10.1186/s13019-015-0370-2.

    18. Tan, Sichuang,Tan, Sipin,Peng, Muyun,Yu, Fenglei.Management of an Ingested Fish Bone in the Lung Using Video-Assist Thoracic Surgery A Case Report[J].Medicine.,2015,94(22):e943-e943.

    19. Hu, Huali,Liu, Wenliang,Tang, Jingqun,Xiong, Wei,Yu, Fenglei.Aorto-Azygous Fistula Complicated by Arteriovenous Aneurysm Treated With Video-Assisted Thoracic Surgery[J].The Annals of Thoracic Surgery: Official Journal of the Society of Thoracic Surgeons and the Southern Thoracic Surgical Association,2015,99(5):E107-E109.

    20. Li, Yunping,Wang, Ranran,Tang, Jingqun,Chen, Chen,Tan, Ling,Wu, Zhongshi,Yu, Fenglei,Wang, Xiang.Progressive Muscle Relaxation Improves Anxiety and Depression of Pulmonary Arterial Hypertension Patients[J].Evidence-based complementary and alternative medicine: eCAM,2015,2015(4):Article ID 792895-Article ID 792895.

    21. Yunping,Li,Ranran,Wang,Jingqun,Tang,Chen,Chen,Ling,Tan,Zhongshi,Wu,Fenglei,Yu,Xiang,Wang.Progressive muscle relaxation improves anxiety and depression of pulmonary arterial hypertension patients.[J].Evidence-based complementary and alternative medicine : eCAM,2015,2015:792895.DOI:10.1155/2015/792895.

    22. Huali,Hu,Wenliang,Liu,Jingqun,Tang,Wei,Xiong,Fenglei,Yu.Aorto-azygous fistula complicated by arteriovenous aneurysm treated with video-assisted thoracic surgery.[J].The Annals of thoracic surgery,2015,99(5):e107-9.DOI:10.1016/j.athoracsur.2015.02.002.

    23. Xiong, Wei,Wang, Li,Yu, Fenglei.Regulation of cellular iron metabolism and its implications in lung cancer progression[J].Medical oncology,2014,31(7):.

    24. Qian,Chen,Li,Wang,Yuchao,Ma,Xianning,Wu,Longyu,Jin,Fenglei,Yu.Increased hepcidin expression in non-small cell lung cancer tissue and serum is associated with clinical stage.[J].Thoracic cancer,2014,5(1):14-24.DOI:10.1111/1759-7714.12046.

    25. Wenliang,Liu,Demiao,Kong,Fenglei,Yu,Bangliang,Yin.A simple technique for pectus bar removal using a modified Nuss procedure.[J].Journal of pediatric surgery,2013,48(5):1137-41.DOI:10.1016/j.jpedsurg.2013.01.052.

    26. Wenliang,Liu,Peng,Xiao,Hengxing,Liang,Ran,An,Gang,Cheng,Fenglei,Yu.[Trachea repair and reconstruction with new composite artificial trachea transplantation].[J].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery,2013,27(3):330-4.

    27. Wen,Hu,Xiang,Wang,Sichuang,Tan,Songqing,Fan,Jun,Liu,Fenglei,Yu,Jingqun,Tang.Large hemangioma in a persistent left superior vena cava.[J].The Thoracic and cardiovascular surgeon,2012,60 Suppl 2:e3-5.DOI:10.1055/s-0032-1330995.

    28. Wenliang,Liu,Fenglei,Yu,Bangliang,Yin,Lu,Deng.[Video-assisted thoracoscopic sympathictomy plus bypass fiber resection for patients with primary palmar hyperhidrosis].[J].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences,2012,37(7):711-3.DOI:10.3969/j.issn.1672-7347.2012.07.011.

    29. Bin,Wang,Mingzhe,Song,Jingqun,Tang,Fenglei,Yu.Sternoclavicular Joint and Sternal Reconstruction With 3-Dimensional Carbon-Fiber Prosthesis.[J].Seminars in thoracic and cardiovascular surgery,32(1):171-173.DOI:10.1053/j.semtcvs.2019.05.013.

    30. 黄奇,谭思创,胡衍,王彬,喻风雷.胸腔镜手术治疗肋骨骨纤维异常增殖症的可行性研究(附15例报告)[J].中国内镜杂志,2022,28(2):82-85.DOI:10.12235/E20210266.

    31. 彭慕云,喻风雷.基于德尔菲法构建胸外科手术难度评价量表[J].中南大学学报(医学版),2022,47(5):655-664.DOI:10.11817/j.issn.1672-7347.2022.200782.

    32. 高阳,李曦哲,张兰军,胡坚,李鹤成,于振涛,喻风雷,张春芳.机器人胸外科日间手术热点问题探讨[J].中华医学杂志,2021,101(29):2271-2275.DOI:10.3760/cma.j.cn112137-20210510-01106.

    33. 谭思创,胡衍,彭慕云,黄奇,胡琪康,喻风雷.一种局部晚期非小细胞肺癌微创淋巴结清扫的改良术式——单中心经验[J].中南大学学报(医学版),2021,46(11):1227-1232.DOI:10.11817/j.issn.1672-7347.2021.200065.

    34. 曾剑,喻风雷,刘文亮.手术治疗右上纵隔肿瘤伴上腔静脉阻塞综合征的临床分析[J].当代医学,2017,23(16):18-21.DOI:10.3969/j.issn.1009-4393.2017.16.007.

    35. 叶曼,李迎霞,喻风雷,张静平.POSSUM、P-POSSUM 及 Thoracoscore 预测胸外科患者术后病死率的评价比较[J].中华胸心血管外科杂志,2016,32(2):99-103.DOI:10.3760/cma.j.issn.1001-4497.2016.02.009.

    36. 胡华利,刘文亮,唐敬群,彭慕云,喻风雷.电视辅助胸腔镜手术治疗降主动脉-奇静脉瘘并血管瘤形成一例[J].中华胸部外科电子杂志,2016,3(1):59-61.DOI:10.3877/cma.j.issn.2095-8773.2016.01.059.

    37. 梁恒星,刘文亮,谭思创,喻风雷.自体心包片修补主动脉食管瘘l例[J].中南大学学报(医学版),2016,41(9):998-1000.DOI:10.11817/j.issn.1672-7347.2016.09.017.

    38. 梁恒星,刘文亮,王翔,喻风雷.恶性胸腺瘤侵犯大血管的手术治疗及术后生存调查[J].中国现代手术学杂志,2013,17(2):142-147.

    39. 刘文亮,孔德淼,喻风雷.胸腔镜与非胸腔镜辅助改良Nuss手术矫治漏斗胸的临床比较[J].中南大学学报(医学版),2013,(8):848-852.DOI:10.3969/j.issn.1672-7347.2013.08.015.

    40. 刘文亮,孔德淼,喻风雷,尹邦良.漏斗胸Nuss术后矫形钢板改良取出技术临床应用的观察分析[J].中南大学学报(医学版),2013,38(3):274-278.DOI:10.3969/j.issn.1672-7347.2013.03.010.

    41. 崔鑫鹏,唐敬群,喻风雷,王翔.巨大后纵隔神经母细胞瘤1例[J].中华胸心血管外科杂志,2012,28(9):566.DOI:10.3760/cma.j.issn.1001-4497.2012.09.020.

    42. 刘文亮,喻风雷,尹邦良,邓露.胸腔镜下T4胸交感神经干加旁路纤维切断术治疗原发性手汗症[J].中南大学学报(医学版),2012,37(7):711-713.DOI:10.3969/j.issn.1672-7347.2012.07.011.

    43. 陈名久,尹邦良,胡建国,喻风雷.经胸骨正中切口切除上肺局部晚期肺癌的临床观察[J].中南大学学报(医学版),2011,36(4):355-358.DOI:10.3969/j.issn.1672-7347.2011.04.014.

    44. [24]谭思创,喻风雷,胡文,唐敬群,王翔,邹敏.全电视胸腔镜肺叶切除术的临床应用(附186例报告)[J].中南大学学报(医学版),2011,36(1):80-83.DOI:10.3969/j.issn.1672-7347.2011.01.013.

    45. 陈龙,喻风雷.BRD7在非小细胞肺癌组织中的表达及临床意义[J].中国肺癌杂志,2011,14(10):830-834.DOI:10.3779/j.issn.1009-3419.2011.10.11.

    46. 刘文亮,喻风雷,尹邦良.非胸腔镜辅助改良Nuss手术矫治漏斗胸[J].重庆医科大学学报,2011,36(8):994-996.

    47. 吴显宁,陈名久,苏丹,喻风雷.肺癌围手术期患者家属焦虑、抑郁状况对患者一般心理状况的影响[J].中国肺癌杂志,2011,14(12):908-911.DOI:10.3779/j.issn.1009-3419.2011.12.02.

    48. 喻风雷.全电视胸腔镜技术(VATS)行肺叶切除112例观察[C].第十届全国胸腔镜及胸部微创外科学术研讨会论文集.2010:46-47.

    49. 刘文亮,喻风雷.胸腔镜辅助Nuss手术在矫治复发性漏斗胸中的应用[J].重庆医科大学学报,2010,35(3):445-447.

    50. 陈晨,尹邦良,魏启幼,胡建国,喻风雷,袁运长,赵元.137例胸腺上皮肿瘤的预后影响因素[J].中南大学学报(医学版),2009,34(4):340-344.DOI:10.3321/j.issn:1672-7347.2009.04.013.

    51. 梁恒星,喻风雷.恶性胸腺瘤的外科治疗进展[J].中国现代手术学杂志,2008,12(6):468-472.

    52. 刘文亮,喻风雷,尹邦良.电视胸腔镜辅助NUSS手术微创治疗漏斗胸[J].中南大学学报(医学版),2008,33(5):443-447.DOI:10.3321/j.issn:1672-7347.2008.05.013.

    53. 刘文亮,喻风雷.肺癌肿瘤干细胞及相关研究进展[J].中国医师杂志,2007,9(3):427-428.DOI:10.3760/cma.j.issn.1008-1372.2007.03.080.

    54. 翟春波,喻风雷,刘文亮,胡建国,周新民.小儿先天性食管闭锁12例临床分析[J].中国医师杂志,2007,9(2):226.DOI:10.3760/cma.j.issn.1008-1372.2007.02.044.

    55. 喻风雷.上腔静脉和/或无名静脉扩大切除及重建在胸部肿瘤中的应用[C].中华医学会第六次全国胸心血管外科学术会议论文集(胸外科分册).2006:.

    56. 张明,喻风雷,胡铁辉,陈名久.胸腔镜辅助小切口肺切除术的临床应用[J].实用医学杂志,2006,22(10):1182-1183.DOI:10.3969/j.issn.1006-5725.2006.10.038.

    57. 翟春波,喻风雷.上纵隔畸胎瘤破入心包1例[J].中华胸心血管外科杂志,2006,22(5):314.DOI:10.3760/cma.j.issn.1001-4497.2006.05.039.

    58. 喻风雷,王翔,陈名久,袁运长,唐滔,张明,吕卫东,胡建国,尹邦良.气管、支气管、心血管成形和(或)选择性C-N3淋巴结清扫治疗肺癌156例外科分析[J].中国医师杂志,2006,8(4):531-532.DOI:10.3760/cma.j.issn.1008-1372.2006.04.055.

    59. 袁运长,喻风雷,尹邦良,胡建国,刘锋.胸段食管癌淋巴结转移156例临床分析[J].中国综合临床,2005,21(10):908-909.DOI:10.3760/cma.j.issn.1008-6315.2005.10.021.

    60. 袁运长,喻风雷,尹邦良,胡建国,刘锋.食管多原发癌的诊断和治疗[J].现代中西医结合杂志,2005,14(9):1184.DOI:10.3969/j.issn.1008-8849.2005.09.049.

    61. 吕卫东,喻风雷,胡铁辉,王翔.胸腔镜肺叶切除术在治疗I期肺癌的应用[J].实用医学杂志,2005,21(20):2282-2283.DOI:10.3969/j.issn.1006-5725.2005.20.023.


    Beberapa Publikasi:

    Berpartisipasi dalam mengedit 3 buku,

    Prestasi dan Penghargaan Akademis:

    Menjadi tuan rumah bagi 12 proyek penelitian ilmiah utama nasional

    Memperoleh 1 paten penemuan nasional;

    Telah melatih 13 lulusan magister dan 12 kandidat doktor.

    Prestasi dan Penghargaan Akademis:

    Memperoleh 9 proyek penelitian ilmiah tingkat provinsi dan kementerian serta satu paten penemuan. Diantaranya, "Penelitian Seri Trakea Buatan" telah didukung oleh proyek-proyek utama dari Departemen Keuangan Provinsi Hunan, Departemen Sains dan Teknologi, dan Kementerian Sains dan Teknologi Tiongkok.

    Penunjukan Editorial dan Akademik:

    Anggota Komite Tetap Cabang Ahli Bedah Toraks dari Asosiasi Dokter Medis Tiongkok

    Anggota Komite Profesional Bedah Toraks Nasional untuk Penilaian Berkala Dokter

    Anggota Komite Profesional Pelatihan Standar Dokter Residen dalam Bedah (Bedah Toraks dan Jantung) dari Asosiasi Dokter Medis Tiongkok

    Ketua Komite Profesional Bedah Toraks dari Asosiasi Medis Provinsi Hunan

    Wakil Ketua Komite Profesional Kanker Paru-Paru dari Asosiasi Anti-Kanker Hunan

    Anggota dewan redaksi buku teks perencanaan nasional "Bedah" edisi ke-3 untuk mahasiswa sarjana pendidikan tinggi umum

    Beliau telah menghadiri 3 konferensi internasional tentang Bedah Toraks dan Jantung Asia di Malaysia, Taiwan, Korea Selatan dan wilayah lainnya.


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